基本資料
姓名 羅慧珍
職稱 教授兼任食營博主任
辦公室分機 02 2905 2547
實驗室分機 02 2905 3768
E-mail 041663@mail.fju.edu.tw
專長
  • 胺基酸代謝
  • 靜脈及腸道營養
  • 代謝症候群
  • 中草藥及保健食品
研究方向
  • 補充營養素於復甦液對出血性休克誘導全身性及標的器官損傷之影響
  • 精胺酸與誘導型一氧化氮合成酶抑制劑aminoguanidine 調控腹膜炎誘導血液及標的器官氧化壓力之比較
  • 植物萃取產品之護肝功能健康食品篩選驗證
  • uSOLA紅麴植萃產品預防脂肪肝試驗
主要學歷
  • 1991-1996 University of Wisconsin-Madison, USA. Department of Nutritional Sciences, Ph.D.
  • 1986-1990 Fu-Jen Catholic University, Taiwan, R.O.C., Department of Nutrition and Food Sciences, BS. Major in Nutritional Sciences.
學術研究成果
  • 2010-2016 期刊論文
  • Lo HC, Wu SC, Li ML, Lee CH. Does pharmacological dose of parenteral arginine have beneficial effect in rats with sub-acute peritonitis? Pediatric Surgery International. 2010 Jun;26(6):625-32. (ISSN:0179-0358, SCI:79/117, IF:1.061, NSC 93-2320-B-309-003)
  • Lo HC, Wang YH, Chiou HY, Lai SH, Yang Y. Relative efficacy of casein or soya protein combined with palm or safflower-seed oil on hyperuricaemia in rats. British Journal of Nutrition. 2010 Mar;104(1):67-75. (ISSN:0007-1145, SCI:21/78, IF:3.342, 96-CCH-IPI-09)
  • Hsiao CC, Lee CH, Tsao LY, Lo HC*. Dose effects of chronically infused nitric oxide synthase inhibitor NG-nitro-l-arginine methyl ester on anabolic response and arginine metabolism in rats with subacute peritonitis. Biol Pharm Bull. 2011 Feb;34(2):177-82. (ISSN:0918-6158, PHARMACOLOGY & PHARMACY, SCI:161/255, IF: 1.828, NSC 93-2320-B-309-003)
  • Lai CH, Teng JF, Hsu TH, Lin FY, Yang PW, Lo HC*. 28-Day Oral Safety Evaluation of Extracellular Polysaccharopeptides Produced in Submerged Culture from the Turkey Tail Medicinal Mushroom Trametes versicolor (L:Fr) Pilát LH-1 in Mice. Int J Med Mushrooms. 2011 May;13(3):227-36 (ISSN:1521-9437, MYCOLOG, SCI:24/22, IF: 0.927, 97-EC-17-A-17-S1-115)
  • Lo HC, Wasser SP. Medicinal mushrooms for glycemic control in diabetes mellitus: history, current status, future perspectives, and unsolved problems. Int J Med Mushrooms. 2011 Nov;13(5):401-26 (ISSN:1521-9437, MYCOLOG, SCI: 24/22, IF: 0.927)
  • Chen YH, Yeh CW, Lo HC, Su SL, Hseu YC, Hsu LS. Generation of reactive oxygen species mediates butein-induced apoptosis in neuroblastoma cells. Oncol Rep. 2012 Apr;27(4):1233-7. (ISSN: 1021-335X, ONCOLOGY, SCI:138/211, IF: 2.301).
  • Lee CH, Hsiao CC, Hung CY, Chang YJ, Lo HC*. Long-term enteral arginine supplementation in rats with intestinal ischemia and reperfusion. J Surg Res. 2012 Jun; 175(1):67-75. (ISSN: 0022-4804,SURGERY, SCI:78/198, IF: 1.936, NSC 98-2320- B-030-003-MY3)
  • Hsiao CC, Lee CH, Tsao LY, Lo HC*. The dose-dependent immunoregulatory effects of the nitric oxide synthase inhibitor NG-nitro-L-arginine methyl ester in rats with sub-acute peritonitis. PLoS One. 2012 Aug;7(8):e42467. (ISSN: 1932-6203, MULTIDISCIPLINARY SCIENCES, SCI:9/57, IF: 3.234, NSC 93-2320-B-309-003)
  • Lo HC, Hsu TH, Wasser SP, Lin FY, Chen YH, Lee CH. Effects of yellow brain culinary-medicinal mushroom, Tremella mesenterica Ritz.:Fr. (higher basidiomycetes), on immune function in normal and type 1 diabetic rats. Int J Med Mushrooms. 2012 October;14(5): 447–57 (ISSN:1521-9437, MYCOLOG, SCI:219/255, IF: 0.927, CCH-4604)
  • Chen YH, Lee CH, Hsu LS, Hsiao CC, Lo HC*. Appropriate dose of parenteral arginine enhances immunity of peripheral blood cells and splenocytes in rats with subacute peritonitis. JPEN J Parenter Enteral Nutr.2012 Nov;36(6):741-9. (ISSN:0148-6071, NUTRITION & DIETETICS, SCI:23/77, IF: 3.151, NSC 93-2320-B-309-003)
  • Hsu WY, Wu CH, Hsieh CTC, Lo HC, Lin JS, Kao MD. Low body weight gain, low white blood cell count and high serum ferritin as markers of poor nutrition and increased risk for preterm delivery. Asia Pac J Clin Nutr. 2013 March;22(1): 90-9 (ISSN:0964-7058, NUTRITION & DIETETICS, SCI:57/77, IF: 1.699)
  • Lo HC, Hsieh C, Lin FY, Hsu TH. A systematic review of the mysterious caterpillar fungus ophiocordyceps sinensis in dong chongxiacao (冬蟲夏草 dōng chóng xià cǎo) and related bioactive ingredients. Journal of Traditional and Complementary Medicine. 2013 March; 3(1): 16-32. (ISSN: 2225-4110)
  • Chen YH, Lee CH, Hsu LS, Lo HC*. Effects of parenteral arginine on oxidative and nitrosative stress in erythrocytes and the gastrocnemius muscle of rats with subacute peritonitis. Nutr Sci J. 2013 April; 38(2):40-9.
  • Lee CH, Hsiao CC, Hung CY, Lo HC*.Combination treatment of parenteral arginine and nitric oxide inhibitor N(G)-nitro-L-arginine methyl ester in rats with peritonitis. J Surg Res. 2013 May 1; 181(1):99-105. (ISSN: 0022-4804, SURGERY, SCI:78/198, IF:1.936, NSC 93-2320-B-309-003)
  • Hsu T-H, Lee C-H, Lin F-Y, Wasser SP, Lo HC.* The fruiting bodies, submerged culture biomass, and acidic polysaccharide glucuronoxylomannan of yellow brain mushroom Tremella mesenterica modulate the immunity of peripheral blood leukocytes and splenocytes in rats with impaired glucose tolerance. Journal of Traditional and Complementary Medicine. (J Tradit Complement Med) 2014; Jan; 4(1), 56-63.
  • Chen YH, Lee CH, Hsiao CC, Hsu LS, Lo HC.* Diverse effects of parenteral arginine on systemic and local oxidant-antioxidant homeostasis and nitrosative stress in rats with subacute peritonitis. J Surg Res. 2014 Mar;187(1):134-41 (ISSN: 0022-4804, SURGERY, SCI:78/198, IF:1.936)
  • Lo HC, Yang RB, Lee CH. Guanylyl cyclase-G modulates jejunal apoptosis and inflammation in mice with intestinal ischemia and reperfusion. PLoS One. 2014 Jul 3;9(7):e101314. (ISSN: 1932-6203, MULTIDISCIPLINARY SCIENCES, SCI:9/57, IF: 3.234, NSC 96-2320-B-309-003-MY2)
  • Chen JZ, Lo HC*, Lin FY, Chang SL, Hsieh C, Liang ZC, Ho WJ, Hsu TH. Effects of medium components and culture conditions on mycelial biomass and the production of bioactive ingredients in submerged culture of Xylaria nigripes (Ascomycetes), a Chinese medicinal fungus. Int J Med Mushrooms. 2014 Oct;16(5):431-47. (ISSN:1521-9437, MYCOLOG, SCI:24/22, IF: 0.927)
  • Chen YH, Lee CH, Hsu TH, Lo HC*. Submerged-culture mycelia and broth of the maitake medicinal mushroom Grifola Frondosa (higher basidiomycetes) alleviate type 2 diabetes-induced alterations in immunocytic function. Int J Med Mushrooms. 2015 17(6): 541–556. (ISSN:1521-9437, MYCOLOG, SCI:24/22,, IF: 0.927)
  • Chen CH, Kang L, Lo HC, Hsu TH, Lin FY, Lin YS, Wang ZJ, Chen ST, Shen CL. Polysaccharides of Trametes versicolor improve bone properties in diabetic rats. J Agric Food Chem. 2015 Oct 28;63(42):9232-8. (ISSN:0021-8561, FOOD SCIENCE & TECHNOLOGY, SCI:13/122, IF: 2.912)
  • Lai CH, Lee CH, Hung CY, Lo HC*. Oral citrulline mitigates inflammation and jejunal damage via the inactivation of neuronal nitric oxide synthase and nuclear factor-κb in intestinal ischemia and reperfusion. JPEN J Parenter Enteral Nutr. (ISSN:0148-6071, NUTRITION & DIETETICS SCI:23/77, IF: 3.151, NSC 98-2320-B-030-003-MY3)
  • 2010-2016 摘要
  • Chiu YW, Lo HC*, Hsu TH, Lin FY. The immuno-regulatory activity of Tremella mesenterica in rats with impaired glucose tolerance. 台灣保健食品學會,台北,摘要PA-029, p62, 2010。
  • 賴春宏、羅慧珍、李建興。比較精胺酸、瓜胺酸及麩醯胺酸改善小腸缺血再灌流引發腸道損傷之效果。台灣靜脈暨腸道營養學會,台北,摘要II-2, 2010。
  • Lo HC, Yang RB, Huang YC, Lai CH. The involvement of guanylyl cyclase-G in intestinal ischemia and reperfusion-induced jejunal apoptosis in mice. Los Angelus, California, USA. FASEBJ. 24(5):1027, 2010 Apr.
  • Lai CH, Teng JF, Hsu TH, Lin FY, Lo, HC. Safety evaluation of extracellular polysaccharopeptides produced from Trametes versicolor LH-1 submerged culture in mice. AFLAS, Taipei, abstract D-5, p163, 2010.
  • 陳建志、黃思齊、張雅雯、羅慧珍、林芳儀、徐泰浩。雲芝菌絲體吸附於天然基材對其胞外多醣肽發酵產程之影響。台灣食品科學技術學會,台中,摘要B-39,2010。
  • Teng JF, Lo HC, Hsu TH, Lin FY. The effects of Trametes versicolor-derived polysaccharopeptides on glucose uptake and insulin signaling pathway. 台灣保健食品學會,台北,摘要PA-027, p65, 2011。
  • 賴春宏、羅慧珍、李建興。補充麸醯胺酸或瓜胺酸減緩小腸缺血再灌流引發之小腸細胞凋亡及發炎反應。台灣靜脈暨腸道營養學會,台北,摘要I-4, 2011。
  • Lo HC, Lee CH. Effects of arginine, ornithine, and citrulline ingestion on immune function in massive bowel resected rats with bowel segment reversal and oral antibiotics. Washington DC, USA. FASEBJ. 25(5):78413, 2011.
  • 徐泰浩、林芳儀、羅慧珍、黃思齊、陳建志、楊士賢、謝建元。天然絲瓜絡載體固定化雲芝菌絲體批次饋料生產胞外醣肽。中國菌物學會,中國青島,摘要P-110,2011。
  • Chen JZ, Lin FY, Lo HC, Hsu TH. The effect of different materials for mycelial immobilization on the production of extracellular polysaccharopeptide from Trametes versicolor. The 49th Annual Meeting of the Agricultural Chemical Society of Taiwan, Taipei, Taiwan Abstract: C-103, 2011.
  • 邱郁雯、羅慧珍。口服給予麩醯胺酸、瓜胺酸及抗氧化劑對大鼠經小腸缺血再灌流誘導之腸道損傷及發炎反應的影響。台灣營養學會,台中,摘要OA-05, p106, 2011。
  • 陳建志、徐泰浩、林芳儀、黃思齊、張雅雯、羅慧珍。雲芝菌絲體吸附於天然基材以連續式發酵對胞外多醣肽產程之影響。生化工程研討會,台北,摘要P1-9, p95, 2011。
  • Chiang JH, Lo HC, Hsu TH, Lin FY. Investigating the efficiency of Trametes versicolor polysaccharopeptides on regulating glucose uptake of muscle cells and hyperglycemia of diabetic rats. International Conference on Food Factors (ICOFF), Taipei, Taiwan Abstract P1-144, 2011.
  • Lo HC, Lee CH. The effects of combination treatment of parenteral arginine and a nitric oxide synthase inhibitor L-NAME on oxidative stress in rats with sub-acute peritonitis. San Diego, California, USA. FASEBJ. 26, 2012 Apr.
  • Chen JZ, Lin FY, Hsu TH, Lo HC, Chen NY. Polysaccharide fractions from the submerged fermentation culture of Trametes versicolor LH1 with characterization and proliferation in PBMC. Proceedings of the 18th congress of the international society for mushroom science. Beijing, China. Abstract p162, Full paper p585-591. 2012 Aug.
  • Lo HC. Parenteral arginine and nitric oxide synthase inhibitor NG-nitro-L-arginine methyl ester in subacute peritonitis: be more or less? Japanese Society of Parenteral and Enteral Nutrition, Kanazawa, Japan, East Asia Travel Grant Session 1-2, Abstract 16, 2013 Feb.
  • Lo HC, Lee CH, Chin SH. The effects of arginine and nitric oxide synthase inhibitors on intestinal damage in guanylyl cyclase-G gene knockout mice with intestinal ischemia and reperfusion. Boston, MA, USA. FASEBJ. 27, 2013 Apr.
  • 賴美如、李建興、邱郁雯、羅慧珍*。精胺酸、瓜胺酸及麩醯胺酸補充劑改善小腸缺血再灌流所誘導遠端器官損傷及發炎反應之效果。台灣靜脈暨腸道營養學會,台中,摘要II-4, 2013 Apr。
  • 賴美如、李建興、邱郁雯、羅慧珍*。2013。口服補充麩醯胺酸、瓜胺酸及抗氧化維生素對小腸缺血再灌流誘導之遠端器官損傷及發炎反應的影響。台灣營養學會,台中,摘要PA-23,p.148,2013 May。
  • Lo HC, Yang Y. Immunocytic profiles and responses of hyperuricemic rats fed with casein or soy protein combined with palm or safflower oil. Granada, Spain. IUNS. PO049, 2013, Sep. Ann Nutr Metab 2013;63(suppl 1):301.
  • 賴春宏、李建興、羅慧珍*。2014。靜脈補充精胺酸及一氧化氮合成酶抑制劑aminoguanidine對亞急性腹膜炎大鼠血液氧化指標及抗氧化酵素活性之影響。台灣靜脈暨腸道營養學會,台中,壁報-2,p.86,2014 Apr。
  • 李裕秀、羅慧珍*、李建興。2014。Effects of arginine-, citrulline-, or glutamine-supplemented resuscitation fluids on hematology and inflammatory
  • Lo HC, Lee CH. The effects of parenteral arginine and aminoguanidine on oxidant-antioxidant homeostasis of organs in rats with subacute peritonitis. San Diego, California, USA. FASEBJ. 28, LB339, 2014 Apr.
  • Li YX, Lo HC*, Lee CH. The effects of resuscitation fluids supplemented with arginine metabolism-associated amino acids on organ injury in rats with hemorrhagic shock.台灣營養學會,新北市,摘要PA-17,p.141,2014 May。
  • Lo HC, Lee TY, Lee CH. Oxidative response of cardiac and gastrocnemius muscle in subacute peritonitis with parenteral arginine and aminoguanidine. Taipei, Taiwan. The 6th Asian Congress of Dietetics. Oral presentation, OP4-1, 2014 Aug.
  • Chen CH, Shen CL, Lo HC, Lin YS. A mushroom polysaccharide improve bone microarchitecture and strength in diabetic rats. The International Osteoporosis Foundation (IOF) Regional 5th Asia-Pacific Osteoporosis Meeting, Taipei 2014 Nov.
  • Lo HC, Lee CH. Differential effects of arginine, citrulline and glutamine in intestinal ischemia and reperfusion-induced immune disorders. Boston, MA, USA. FASEBJ. 29, LB593.6, 2015 March.
  • Huang FH, Lee CH, Lo HC. The impacts of arginine-, glutamine-, and amino acid mixture-supplemented resuscitation fluids on trauma-hemorrhage shock-induced inflammatory responses and organ damages in rats. 台灣靜脈暨腸道營養醫學會,台中,壁報-29,p.56,2015 Apr。
  • 專利: 細胞吸收葡萄糖效率之檢驗方法/Method for Assaying the Efficiency of Cell Glucose Uptake」。中華民國專利,發明第I 424057號。發明人羅慧珍。專利權期間2014/01/21至2030/06/02。
  • 技術轉移:以人類肝臟細胞株篩選具調節血糖功能之活性成份驗證平台。中華真菌股份有限公司。99年9月
  • 技術轉移:利用小鼠肌肉細胞株篩選具調節葡萄糖汲取效用之活性成份驗證平台。台灣醣肽科技股份有限公司。100年11月
  • 專門著作: 膳食療養學(三版),第十五章“保健食品與健康” ,p.15-2~p.15-32。2011年9月華格納出版社。
  • 專門著作: “國人膳食營養素參考攝取量及其說明”,第七版,蛋白質,p.48-67。2012年5月行政院衛生署食品藥物管理局。
  • 專門著作: 膳食療養學(四版),第十五章“保健食品與健康” ,p.15-2~p.15-34。2014年8月華格納出版社。
  • 專門著作: 2015台灣慢性腎臟病臨床診療指引專書,第六章“成人慢性腎臟病之營養照護”,p.122~p.154。2015年10月財團法人國家衛生研究院。
  • 2010 台灣營養學會第三十六屆傑出研究獎
  • 2011 100年度國科會獎勵特殊優秀人才獎
  • 2012 輔仁大學100學年度教學績優教師獎
  • 2012 101年度國科會獎勵特殊優秀人才獎
  • 2012 輔仁大學101學年度導師班級經營工作成果獎
  • 2013 102年度國科會獎勵特殊優秀人才獎
  • 2014 103年度國科會獎勵特殊優秀人才獎
  • 2015 104年度國科會獎勵特殊優秀人才獎
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